Unformatted text preview: Alkylation of Benzene Friedel-Crafts Alkylation of Benzene
Reaction equation: Mechanism of formation on the electrophile: Mechanism of Friedel-Crafts Alkylation
Step 1. Addition of the electrophile. Step 2. Deprotonation. Mechanism of Friedel-Crafts Alkylation
Primary and methyl cations are too unstable to be formed so
the Lewis acid-base complex is the effective electrophile. Friedel-Crafts Alkylation and Rearrangements
Rearrangements occur especially with primary alkyl
halides. The electrophile is formed by hydride migration to form a more
stable cation. Alternative Sources for Carbocat...
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This note was uploaded on 03/22/2014 for the course CHEM 330 taught by Professor Shen during the Fall '08 term at Northern Illinois University.
- Fall '08