Friedrich whler friedrich theconceptualchasm

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Unformatted text preview: ess molecules to produce energy Considerable time, effort and money are expended in attempting to find out what is happening inside this box. Friedrich Wöhler Friedrich The conceptual chasm between in vivo processes and in vitro analysis, between life and the test tube, was not bridged until 1828 when Friedrich Wöhler ( July 31, 1800 ­ September 23, 1882) synthesized urea in the absence of any ‘vital force’ or living organism. Wöhler had discovered that urea could be produced by evaporating an isomeric solution of ammonium cyanate. This was the first ‘organic’synthesis, a milestone in clinical chemistry, a bridge between the ‘organic’ and ‘inorganic’ worlds, between the living body and the laboratory. This was the first proof that The complex processes occurring within the human body could be understood in terms of chemical procedures that could be carried out in vitro. This work removed the requirement for any mysterious ‘vital force’ that separated in vivo biochemistry from in vitro chemistry Vital force Vital Leading physiologis...
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