This preview shows page 1. Sign up to view the full content.
Unformatted text preview: be the first marker to be released from damaged cells ► Troponin I Contractile protein associated with cardiac and skeletal tissue Two forms … Troponin I and Troponin T Troponin I from cardiac tissue has a unique antigenic structure that differentiates it from skeletal Troponin I and facilitates its measurement Of all the cardiac markers , Troponin I is the most specific for cardiac injury CKMB
CKMB Isoenzyme found in cardiac and skeletal tissue Plasma CKMB concentrations are increased in AMI and various forms of skeletal muscle trauma Although not absolutely specific, very high concentrations in cardiac tissue make it a good marker for AMI B Type Natremic Protein ( BNP )
► Increased plasma BNP is associated with Congestive Heart Failure (CHF ) ► CHF is one of the most common reasons for hospitalization in patients greater than 70 years old ► BNP assays are often ordered with AMI markers to...
View Full Document
- Spring '14