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Review of Hardy-Weinberg Equation
Consider a gene with two alleles R and r. R is dominant, r is recessive. Frequency for R is p, for r is q.
Using the Hardy-Weinberg equation, the relative proportion of the RR, Rr, and rr genotypes are p2, 2pq, and q2 respectively.
p2 + 2pq + q2 = 1
Adapting the Hardy-Weinberg Equation to model selection
Fitness coefficient is s
Because R is completely dominant, the fitness for RR and Rr are the same and is 1+ s. The fitness for rr is 1.
In this model, selection operates on the ratios calculated by the Hardy-Weinberg Equation.
Instead of the relative proportion being p2 + 2pq + q2 = 1, after selection, the relative proportions are p2(1 + s) + 2pq(1 + s) + q2
The next generation of p can be calculated by counting up the total number of R alleles and dividing by the total number of all
alleles (twice the number of individuals because of diploidy.)
Next generation p =...
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This lab report was uploaded on 03/26/2014 for the course BIOL 1407 taught by Professor Staff during the Spring '08 term at Blinn College.
- Spring '08