Alterations in Blood Flow-patho

Flow may be mediated by hormonal changes food may

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Unformatted text preview: dden, smooth muscle that results in an obstruction to flow. flow. May be mediated by hormonal changes, food May additives, or environmental factors. additives, Manifestations include: – Angina (varilant) – Hemorrhagic stroke- blood vessel bursts. Hemorrhagic Hypertension – Migraine headaches---vasodilatation following Migraine cerebral vasospasm (spasm causes the pain). cerebral Inflammation Can increase risk of thrombotic process Vasculitis—inflammation of the intima of Vasculitis—inflammation an artery an Phlebitis—inflammation of the lining of a Phlebitis—inflammation vein vein Arteritis (angiitis)—inflammatory process Arteritis of autoimmune origin in arteries of Inflammation Inflammation Can increase risk of thrombotic process Vasculitis—inflammation of the intima of —inflammation an artery an Phlebitis—inflammation of the lining of a —inflammation vein vein Arteritis—inflammatory process of —inflammatory autoimmune origin in arteries autoimmune Mechanical Compression Mechanical Obstruction of blood flow due to trauma, constriction, swelling. May lead to hypoxia, ischemia, or necrosis of tissue. External forces to the vascular system may result in partial or complete obstruction. May be caused by: • Trauma • Tight casts, dressings, or stockings • Compartment syndrome- fluid goes where its not supposed to be (ex: blister) Alterations in Arterial Flow Alterations in arterial flow result from: Obstruction • • • • • Arteriosclerosis/atherosclerosis Inflammation Vasospasm Thrombi/emboli Acute occlusion Mechanical alterations • Arteriovenous fistulas • Aneurysms Arteriosclerosis/Atherosclerosis Arteriosclerosis/Atherosclerosis Arteriosclerosis is a generic term meaning “hardening of the arteries” which is characterized by thickening and lumen narrowing of small arteries. (small vessels and vessels don’t dilate) Atherosclerosis affect intermediate-sized and large vessels in which lipids collect along the intimal surface producing a narrowing and reduction in blood flow/inflammatory response. Underlying pathologic conditions leading to hypertension, cardiac and renal disease, peripheral arterial disease, and stroke Etiology for Atherosclerosis Etiology Effec...
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This document was uploaded on 03/25/2014.

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