Drugs for Pain Opiods and Headaches-pharm

pain assessment slide 49 respirations allergies any

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Unformatted text preview: You could give her an ice patch. 3. What serious adverse effect is possible if she receives too much MS? What, if anything, can be given to treat this? 1. She could have respiratory depression. You would take a set of vital signs Critical Thinking Question You are caring for Mr. D. who returned from surgery 2 hours ago. He is requesting a pain medication. Morphine is ordered for pain. It is important to asses Mr. D. for what before giving the pain medication? - You need to know his pain level, intensity, duration, etc.. (pain assessment-slide 49), respirations, allergies, any previous drugs Critical Thinking Question Why would opioid analgesics be contraindicated in a client with chronic lung disease? It can cause respiratory depression, which could impiar patient from breathing Other Strong Opioid Agonists • Fentanyl---(Sublimaze, Duragesic) – 100 times the potency of morphine- administer 100 in micrograms – Five formulations in three routes • Parenteral – Surgical anesthesia • Transdermal – Patch – heat acceleration Patch – Iontophoretic system – needle-free Iontophoretic • Transmucosal – Lozenge on a stick – Buccal tablets Other Strong Opioid Agonists Other • Alfentanil--- (Alfenta) and Sufentanil l--(Sufenta) (Sufenta) • Remifentanil--- (Ultiva) • Meperidine--- (Demerol) – – – Short half-life Interacts adversely with several other drugs Toxic metabolite accumulation • Methadone--- (Dolophine) – Tx for pain and opioid addicts Other Strong Opioid Agonists Other • Heroin – – – Used legally in Europe to relieve pain High abuse liability Not more effective than other opioids • Hydromorphone (Dilaudid), oxymorphone (Opana), and levorphanol (Levo-Dromoran) (Opana), Moderate to Strong Opioid Agonists • Similar to morphine in most respects – Produce analgesia, sedation, euphoria – Can cause: • Respiratory depression, constipation, urinary Respiratory retention, cough suppression, and miosis retention, – Can be reversed with naloxone • Different from morphine – Produce less analgesia and respiratory Produce depression than morphine depression – Somewhat lower potential for abuse Moderate to Strong Opioid Agonists Agonists Codeine – Actions and uses • • • 10% converts to morphine in liver Pain and cough suppression Problem with CYP2D6 – Preparations, dosage, and administration • Usually PO (formulated alone or with aspirin or Usually acetaminophen) acetaminophen) • 30 mg produces same effect as 325 mg 30 acetaminophen acetaminophen Moderate to Strong Opioid Agonists Agonists Oxycodone – Analgesic actions equivalent to those of Analgesic codeine codeine – Aspirin combo (Percodan) – Acetaminophen combo (Percocet/Roxicet) – Ibuprofen combo (Combunox) – A long-acting analgesic • Immediate release Immediate • Controlled release (OxyContin) Moderate to Strong Opioid Agonists Agonists Hydrocodone (Vicodin, Lortab) – Most widely prescribed drug in the United Most States States – Combined with aspirin, acetaminophen, or Combined ibuprofen ibuprofen Propoxyphene (Darvon) – Analgesic effect equal to that of aspirin – Combined with aspirin or acetaminophen Agonist-Antagonist Opioids Agonist-Antagonist Pentazocine (Talwin) – Actions and uses – Preparations, dosage, and administ...
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