Anti-inflamm Antiallergic Immunologic Drugs- pharm

Adrenals will adrenal forget to work again when given

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Unformatted text preview: y system in neonates Pharmacology of the Glucocorticoids Pharmacology Effects on metabolism and electrolytes Anti-inflammatory and immunosuppressant effects Therapeutic uses in nonendocrine disorders – – – – – – – – – – Rheumatoid arthritis Systemic lupus erythematosus Inflammatory bowel disease Miscellaneous inflammatory disorders Allergic conditions Asthma Dermatologic disorders- rash Dermatologic Neoplasms Suppression of allograft rejection Prevention of respiratory distress syndrome Pharmacology of the Glucocorticoids Pharmacology Adverse effects – Adrenal insufficiency: mineralcorticoids. Adrenals will Adrenal forget to work again when given glucocorticoids (taper the dose, big then smaller) the – Osteoporosis and resultant fractures – Infection – Glucose intolerance – Myopathy- muscles don’t work work – Fluid and electrolyte disturbances – Growth retardation – Psychological disturbances – Cataracts and glaucoma – Peptic ulcer disease – Iatrogenic Cushing’s syndrome Pharmacology of the Glucocorticoids Pharmacology Contraindications – Patients with systemic fungal infections in the Patients blood stream. This grows with suppressed immune response. – Those receiving live virus vaccines – Use with caution in pediatric patients and Use pregnancy/breast-feeding pregnancy/breast-feeding Pharmacology of the Glucocorticoids Pharmacology Adrenal suppression – Why it can develop – Adrenal suppression and physiologic st...
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This document was uploaded on 03/25/2014.

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