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Anti-inflamm Antiallergic Immunologic Drugs- pharm

Chlor trimeton clemastine tavist allergy

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Unformatted text preview: ysrhythmias Rare H1 Antagonists Drug interactions – CNS depressants – Ex: alcohol Ex: Acute toxicity – Large margin of safety- half life is short Large – Widespread availability of drugs – CNS and anticholinergic reactions H1 Antagonists—First Generation Generation First generation (sedating) – Brompheniramine (Brovex) – Chlorpheniramine (Chlor-Trimeton) – Clemastine (Tavist Allergy) – Diphenhydramine (Benadryl)** – Hydroxyzine (Vistaril) – Phenindamine (Nolahist) – Promethazine (Phenergan) H1 Antagonists—Second Generation Second generation (nonsedating) – Fexofenadine (Allegra) – Cetirizine (Zyrtec) – Loratadine (Claritin, Tavist ND, Alavert) – Desloratadine (Clarinex) – Levocetrizine (Xyzal) – Azelastine (Astelin)(nasal only) – Olopatadine (Patanase)(nasal only) High-Risk Patients High-Risk Antihistamines contraindicated Antihistamines – During third trimester of pregnancy – Nursing mothers – Newborn infants- don’t want in breast milk want – Histamine to a pregnant mom could mess with Histamine hormones (preterm labor) hormones – Dry...
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