Anti-inflamm Antiallergic Immunologic Drugs- pharm

Explain immune system immune key feature of the

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Unformatted text preview: . Explain IMMUNE SYSTEM IMMUNE Key feature of the immune response is the ability of the Key lymphocytes to recognize foreign proteins (antigens). lymphocytes Lymphocytes are derived from bone marrow stem cells. T lymphocytes develop in the thymus. B lymphocytes develop in the bone marrow. Produce antibodies. Two types of immune responses – Natural immunity (innate) – Specific acquired immunity Cell-mediated Antibody-mediated – humoral Antibody-mediated The process of acquired immunity. The Immune System: Cells Immune B Lymphocytes (B cells) • Make antibodies Make Cytolytic T lymphocytes • Do not produce antibodies Do • Attach and kill target cells Attach Helper T lymphocytes – Helper T cells, CD4 cells Required for an effective immune response Antibody production by B cells Promote delayed-type hypersensitivity (DTH) Activation of cytolytic T cells Immune System: Cells Immune Macrophages – Begin in bone marrow, enter blood as Begin monocytes, and infiltrate tissues, where they evolve into macrophages evolve – Principal scavengers of the body – Specific acquired immunity Specific Activation of T cells Activation Final mediators of DTH Phagocytize cells tagged with antibodies – Also play key roles in natural immunity and Also inflammation inflammation Immune System: Cells Immune Mast cells and basophils – Mediate immediate hypersensitivity reactions Neutrophils (polymorphonuclear Neutrophils leukocytes) leukocytes) – P...
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This document was uploaded on 03/25/2014.

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