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Every generation r doubling you replace it the enzyme

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Unformatted text preview: rase. Chromosome shortening is prevented in some cell types which have a telomerase enzyme (adds telomere repeats to chromosome ends) 13 BIO 1140 Unit 2-1:Replication It occurs at the end where we have discontinuous synthesis. We can make a primer b/c the other side comes right to the end and remove the primer with RNAase H. DNA Ends, the Problem 14 BIO 1140 Unit 2-1:Replication DNA Ends, the Solution: Adding Telomere Repeats Did you know that other ways of protecting the ends can be found in different species?? 15 There is a complex that recognizes the ends and the ends have a simple sequence and it carries its own template. The primer is the end and the template is the piece thats carried by telomerase (it has its own enzyme activity and carries its own template). The template is complementary to the sequence at the end of our chromosomes. It adds on one repeat unit, but this doesn't add a lot of protection. It extends and shifts back again. The ratchet mechanism. Fig. 13-14, p. 286 see image Mt and ecoli don't have this problem because they are circular. BIO 1140 Unit 2-1:Replication DNA Synthesis Q? What happens when you need more or faster DNA synthesis? Begins at sites that act as replication origins (ori, ars) Proceeds from the origins as two replication forks moving in opposite directions Control the number of replication origins. DNA enzymes go at a certain rate and we cannot make them go at a certain rate. So we recruit more start places (ars). M...
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