Replication begins at replication origins ori ars rna

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Unformatted text preview: rigins (ori, ars). RNA primers provide the starting point for DNA polymerase to begin synthesizing a new DNA chain Telomerases solve a specialized replication problem at the ends of linear DNA molecules 3 DNA polymerases require a primer to initiate synthesis. The primer can be a suitable DNA molecule, one that has a 3’OH, which can be extended. In the absence of a primer, one must be provided de novo. RNA polymerases can synthesize a primer (RNA) de novo. Hence RNA polymerases are used to initiate replication, then it switches to DNA-we need to account for that in the model. This leads to others problems that relate to how the cell deals with these short RNAs. BIO 1140 Unit 2-1:Replication BASIC PROBLEM: DNA polymerase cannot start synthesis de novo DNA polymerases require a primer to initiate synthesis. The primer can be a suitable DNA molecule, one that has a Understanding these extended. 3’OH, which can be examples allows you to In the absence of a primer, one must be provided d will predict whate novo. RNA polymerases can synthesize a primer (RNA) happen when. Hence RNA polymerases de novo a new replicon isare used to initiate replication. encountered This leads to others problems that relate to how the cell deals with these short RNAs. 4 BIO 1140 Unit 2-1:Replication DNA Replication in Eucaryotes Key Points to PONDER Why do you need 3 types of DNA synthesis for a chromosome? (and multiple DNA polymerases in the cell?)...
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This note was uploaded on 03/26/2014 for the course BIO 1140 taught by Professor Fenwick during the Winter '07 term at University of Ottawa.

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