CytochromeP450 - Cytochrome P450 Interaction...

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Cytochrome P450 Interaction Table CYP1A2 ----Substrates----- -----Inhibitors------ ----Inducers---- acetaminophen amitriptyline aprepitant asenapine bendamustine caffeine chlordiazepoxide cinacalcet clomipramine clopidogrel clozapine cyclobenzaprine desipramine diazepam duloxetine erlotinib estradiol flutamide fluvoxamine haloperidol imipramine levobupivacaine methadone mexiletine mirtazapine naproxen nortriptyline olanzapine ondansetron propafenone propranolol ramelteon rasagiline riluzole ropinirole ropivacaine tacrine theophylline tizanidine verapamil (R)-warfarin zileuton zolmitriptan acyclovir amiodarone cimetidine ciprofloxacin citalopram echinacea ethinyl estradiol famotidine fluvoxamine isoniazid methoxsalen mexiletine norfloxacin omeprazole oral contraceptives propafenone tacrine verapamil zafirlukast zileuton carbamazepine charbroiled food lansoprazole omeprazole phenobarbital phenytoin primidone rifampin ritonavir smoking St. John's wort tipranavir/ritonavir CYP28A ----Substrates----- -----Inhibitors------ ----Inducers---- amiodarone benzphetamine carbamazepine docetaxel fluvastatin isotretinoin lapatinib paclitaxel phenytoin pioglitazone repaglinide retinoic acid retinol rosiglitazone tolbutamide tretinoin verapamil warfarin zopiclone atazanavir gemfibrozil montelukast nicardipine nilotinib quercetin sorafenib sulfinpyrazone trimethoprim carbamazepine nilotinib phenobarbital rifabutin rifampicin rifampin CYP2C9 ----Substrates----- -----Inhibitors------ ----Inducers---- amitriptyline carvedilol celecoxib clomipramine desogestrel diazepam diclofenac dronabinol etravirine fluoxetine flurbiprofen fluvastatin formoterol glimepiride glipizide glyburide ibuprofen imipramine indomethacin irbesartan losartan mefenamic acid meloxicam montelukast naproxen nateglinide omeprazole phenytoin piroxicam ramelteon rosiglitazone sildenafil sulfamethoxazole tamoxifen tolbutamide torsemide valdecoxib valsartan vardenafil voriconazole (S)-warfarin zafirlukast zileuton amiodarone clopidogrel cotrimoxazole cranberry delavirdine efavirenz etravirine fenofibrate
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