Notes Principles of Biology Notes eukaryotic and pro

Notes Principles of Biology Notes eukaryotic and pro -...

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Notes Principles of Biology 02/10/14 Differences between eukaryotic and prokaryotic flagella Eukaryotic Ring of microtubules (tubulin) 9 + 2 microtubule axoneme Whip (refers to motion of flagella) Prokaryotic Flagellin Propeller Secondary endosymbiosis: Unicellular organisms can be acquired by another eukaryote Endosymbiosis with green alga symbiont The nucleus of the endosymbiont is lost (but many genes are transferred to the host nucleus) Some kinetoplastids are important parasites Trypanosoma brucei causes sleeping sickness Trypanosoma cruzi causes Chagas’ disease Leishmania major causes leishmaniasis Two-host life cycle of T. brucei Host#1: Tsetse fly (midgut and salivary gland)
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Unformatted text preview: • Host#2: Human or other mammal (bloodstream) T. brucei surface coat • Monolayer of ~10 7 molecules of a single glycoprotein (VSG) • VSG contain a variable region • only one VSG variant is produced at any one time • >1,000 VSG sequences • Immune system recognizes pathogen, by looking at surface receptors of pathogen. • This organism can CHANGE its surface proteins at regular intervals Antigenic variation • =a mechanism to escapes the host immune response • At regular intervals, T .brucei switches to a new VSG • Periodicity of the symptoms Endosymbiosis with red alga symbiont • In some cases, plastid loses ability to perform photosynthesis...
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  • Spring '14
  • Eichenberger
  • Biology, Bacteria, red alga symbiont, VSG sequences, VSG variant

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