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Unformatted text preview: Various mechanisms • Two examples of persistence after phagocytosis: • Listeria monocytogenes (listeriosis) • Mycobacterium tuberculosis (tuberculosis) • Bacteria and infectious agents have adapted. . (2 examples) • Pregnant woman shouldn’t have cheese? • 2 stages of tuburculosis (primary, then secondary stage) Immune evasion by lysis of phagosome • Pore formation in the phagosome by LLO (listeriolysin O) = protein expressed by the pathogen • High temperature (37 degrees) + food = good conditions • Actin-dependent movement • Uses host actin for movement • (bacterium only provides the anchor site, ActA) • Will move from cytoplasm to cytoplasm • Actin act A • Bacteria can manipulates hosts resources...
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- Spring '14
- Biology, 37 degrees, cell lysis, microbial cell lysis