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Unformatted text preview: • Cellular defenses (e.g. phagocytosis) • Unique to vertebrates: • Inflammatory response • Natural killer cells • Interferons (inhibition of viral infections) • Skin is first-line defense • Immunity is found in every living organism • Whenever there is an action, there is a response. Barrier defenses in humans • Body fluids (saliva, tears, mucus) • Skin Mucous membranes • of the respiratory, urinary, and reproductive tracts • Low pH (acidity) of skin and the digestive system PRMs: p attern r ecognition m olecules • Toll-Like Receptors (TLRs) • (usually found on phagocytes) • Usually leads to creation of cytokines (hormones of immune system) • One TLR recognizes DNA another recognizes RNA • This one recognizes CpG DNA •...
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- Spring '14