Notes Anatomy & Physiology II Endocrine System 7 Regulation of hGH

Notes Anatomy & Physiology II Endocrine System 7 Regulation of hGH

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Anatomy & Physiology II AHS 132 Chapter 18 The Endocrine System Regulation of hGH • Low blood sugar stimulates release of GHRH from hypothalamus – anterior pituitary releases more hGH, more glycogen broken down into glucose by liver cells • High blood sugar stimulates release of GHIH from hypothalamus – less hGH from anterior pituitary, glycogen does not breakdown into glucose Somatostatin : Inhibits release of GH Diabetogenic Effect of Human Growth Hormone • Excess of growth hormone – raises blood glucose concentration – pancreas releases insulin continually – beta-cell burnout • Diabetogenic effect – causes diabetes mellitus if no insulin activity can occur eventually Thyroid Stimulating Hormone (TSH) • Hypothalamus regulates thyrotrophic cells • Thyrotrophic cells produce TSH • TSH stimulates the synthesis & secretion of: – T3 and T4 • Metabolic rate stimulated Follicle Stimulating Hormone (FSH) • Releasing hormone from hypothalamus controls gonadotrophs
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  • Spring '14
  • AlbertGrazia
  • Anterior pituitary, thyroid stimulating hormone, human growth hormone

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