Notes Anatomy & Physiology II Endocrine System 3 Lipid Derivatives

Notes Anatomy & Physiology II Endocrine System 3 Lipid Derivatives

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Anatomy & Physiology II AHS 132 Chapter 18 The Endocrine System Lipid Derivatives Steroid hormones - derived from cholesterol – Released by: • The reproductive organs (androgens by the testes in males, estrogens and progestins by the ovaries in females) • The cortex of the adrenal glands (corticosteroids) • The kidneys (calcitriol) – Because circulating steroid hormones are bound to specific transport proteins in the plasma: • They remain in circulation longer than secreted peptide hormones Secretion and Distribution of Hormones Free Hormones – Remain functional for less than 1 hour 1. Diffuse out of bloodstream and bind to receptors on target cells 2. Are broken down and absorbed by cells of liver or kidneys 3. Are broken down by enzymes in plasma or interstitial fluids • Thyroid and Steroid Hormones – Remain in circulation much longer because most are “bound” – Enter bloodstream •More than 99% become attached to special transport proteins
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  • Spring '14
  • AlbertGrazia
  • Endocrine System, Anatomy & Physiology II, steroid hormones

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