KIN 405 Lecture 21 - Exercise(in(Special(Popula1ons Cancer...

Info icon This preview shows pages 1–10. Sign up to view the full content.

Exercise in Special Popula1ons Cancer ICU
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Changes in Muscle ChangesinFat Implica5ons of Body Composi5on Changes Obesity Impaired glucose tolerance, dyslipidemia ! increased risk of Sarcopenia Increased immune dysfunc1on, hospitaliza1on rates Increased risk of falls & fractures Increased mortality
Image of page 2
Outcomes of Muscle Atrophy Risk of falls • Poten1al fractures • Impaired ADL • Func1onal disabili1es Metabolic Disorders • Dyslipidemia • Osteoporosis • Arthri1s Immune dysA func5on • Complica1ons • Increased Hospital Length of Stay Mortality
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

• S1mulated by cor1sol, epinephrine, glucagon, inflamma1on • Inhibited by insulin, IGFI1, GH, testosterone • Reduced caloric & protein intake • S1mulated by insulin, IGFI1, GH, testosterone • Inhibited by cor1sol, epinephrine, glucagon • Increased protein intake • Amino acids (BCAA, gln) • Increased caloric intake Protein Synthesis Breakdown Protein
Image of page 4
Exercise & Cancer
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Body Composition Through the Cancer Trajectory Palliation Incidence Treatment •Breast •Prostate •Colorectal and other GI •Lung •Pancreatic •Head & Neck •Colorectal Obesity Fat Gain & Muscle Loss Fat Loss & Muscle Loss Disease Progression
Image of page 6
Survival Treatment Response Treatment Toxicity Morbidity in survivorship Changes in fat Changes in muscle Body Composition Implications in Cancer Exercise may prevent or partially reverse or totally reverse the detrimental body composition changes that occur with cancer
Image of page 7

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Dietary Considera1ons Maintain caloric balance – especially for cancers that are prone to involuntary weight loss TEE = REE x ! this increases for an ac1ve cancer pa1ent Enhance protein intake – pa1ents are not generally taking in enough protein Recommended intake: g / kg / day May need even more with weight training
Image of page 8
Dietary Considera1ons Factors to consider:
Image of page 9

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

Image of page 10
This is the end of the preview. Sign up to access the rest of the document.
  • Fall '12
  • MarinaMourtzakis
  • Physical exercise, muscle atrophy, sarcopenia

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern