KIN 405 Lecture 4 - the ability or capacity to perform work...

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the ability or capacity to perform work.”
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ATP Homeostasis ATP Production and Utilization ATP Utilization ATP Production High Energy Phosphate Transfer Oxidative Phosphorylation Na + /K + ATPase Actin-myosin ATPase Mitochondrial ATPase Other processes??
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ENERGY ACTIVITY TYPE INTENSITY DURATION Varied sources & proportions Different energy systems HEPT Oxidative Nutrition ATP
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High Energy Phosphate Transfer (HEPT) ! Primary energy producer for short-term, high intensity activities. ! ! Low capacity to regenerate ! Active at onset of exercise regardless of intensity ! However, intensity will determine how much ATP is generated by the HEPT system, as there is a high demand of ATP with increased intensity ! ATP +H 2 O ! ADP + Pi + H + + Energy (ATPase) ! PCr + ADP + H + ATP + Cr (Creatine Kinase) ! 2 ADP ATP + AMP (Adenylate Kinase)
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Glycogenolysis / Glycolysis ! Breakdown of muscle glycogen and/or glucose to produce ATP ! is end product glycolysis • anaerobic ATP production (pyruvate converted to lactate) accelerated glycolysis / mismatch between pyruvate supply / utilization oxidative ATP production (via PDH)
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Oxidative Metabolism Primary source of ATP at rest and during prolonged low-intensity activity. High Capacity to generate ATP Fat and carbohydrate are primary substrates Higher intensity: almost 100% carbohydrate Muscle or liver glycogen Prolonged submax: shift toward fat Acetyl-CoA
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  • Fall '12
  • MarinaMourtzakis
  • Energy, Adenosine triphosphate, Anaerobic ATP Production

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