Exam.1.07.KEY

Exam.1.07.KEY - NAME _ BIOLOGICAL SCIENCES 110-B DR....

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1 NAME _______________________________________ BIOLOGICAL SCIENCES 110-B DR. JOHNSON'S SECTION Spring 2007 - FIRST EXAM Jan. 31, 2007 PRINT YOUR NAME (LAST NAME FIRST) ON THE COMPUTER ANSWER SHEET AND BLACKEN THE CORRESPONDING BUBBLES I. Multiple choice (3 points each): Fill in the circles corresponding with your name and I.D. number. Read each of the following questions carefully. Each question has only one best answer. 1. Homeotic genes are very similar in structure and function in organisms ranging from fruit flies to mammals. This is most likely because: A) When evolution creates a mutation to solve a problem, it always selects the simplest solution. B) Evolution is a conservative process and can only work with existing genetic variation. C) Evolution cannot occur rapidly, even with very strong selective pressures. D) Homeotic genes are critically important for the process of meiosis and gametogenesis. E) None of the above 2. Which of the following are chemical messengers that pass through the plasma membrane of cells and activate receptors and/or enzymes in the cytoplasm? A) insulin B) estradiol C) testosterone D) glucagon E) nitric oxide (NO) F) B and C only G) C and D only H) three or more of the above (A-E) 3. Studies on epinephrine by Earl Sutherland have shown that this signal molecule . . . A) passes through the plasma membrane of cells and binds to an intracellular receptor. B) lowers blood glucose by binding to liver cells. C) interacts with insulin inside muscle cells. D) interacts directly with the soluble fraction of liver cells (the “supernatant” after centrifugation of a liver cell extract) to promote glycogen breakdown. E) interacts directly with the particulate fraction of liver cells (the “pellet” after centrifugation of a liver cell extract) to promote the synthesis of cyclic AMP. F) more than one of the above (A-E) is true.
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2 4. Which of the following are NOT necessary for terminating the effect of glucagon on liver cells: A) phosphatase activity B) phosphodiesterase activity C) phospholipase activity D) the regulatory subunit of protein kinase A E) hydrolysis of GTP by the α subunit of the G-protein 5. Which of the following would be inhibited by a drug that specifically blocks the addition of phosphate groups to proteins? A) steroid hormone signaling B) diacylglycerol (DAG) activation of Protein Kinase C (PKC) C) G-protein mediated activation of adenylyl cyclase D) phosphatase activity E) receptor tyrosine kinase activity 6. One reason a person might be severely overweight is low metabolic activity caused by: A) under-secretion of thyroxine. B) defect in hormone release from the posterior pituitary. C) a lower than normal level of insulin-like growth factors. D) under-secretion of oxytocin.
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This note was uploaded on 04/07/2008 for the course BSCI 110B taught by Professor Due during the Spring '08 term at Vanderbilt.

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Exam.1.07.KEY - NAME _ BIOLOGICAL SCIENCES 110-B DR....

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