Bio 105 Chapter 20 reading

Bio 105 Chapter 20 reading - 389-396 Chapter 20Cancer...

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389-396: Chapter 20—Cancer Cancer: disease in which cells divide uncontrollably, often invading other parts of the body o Not all abnormal cellular proliferation is cancerous Benign vs. malignant tumors o Benign: reach a certain size and then stop growing Pose no significant medical problems o Malignant: continue to grow and often spread to other parts of the body, where they may destroy vital organs Only neurons and muscle cells can’t divide Metastasis: spread of cells from one region of the body to another (primary secondary tumors) o Cancer cells often migrate to other sites o Form secondary tumors Cancer cells: cell-cell adhesion molecules missing or altered Most common site for metastasis = lungs o Extensive capillary network 2 nd most common is liver Prostate cancer cells settle in bones How cancers form o 1. Conversion
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Mutation from co-carcinogen in one of 50 genes that control replication Proto-oncogenes: when mutated and not repaired,
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