NMR_F13_spectra - NMR spectrum of Alanine Assignment...

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11/14/13 1 Assignment Splitting Position (ppm) C ! H C " H 3 multiplet 4.35 C " H 3 C ! H doublet 1.3 NMR spectrum of Alanine NMR spectrum of valine
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11/14/13 2 This is the spectrum of a. Leucine b. Serine c. Threonine d. Histidine Threonine Assignment Splitting Position (ppm) C ! H C " H doublet 3.6 C " H C # H3 and C ! multiplet 4.3 C # H 3 C " H doublet 1.3
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11/14/13 3 NMR spectrum of leucine This is the spectrum of a. Isoleucine b. Serine c. Methonine d. Histidine
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11/14/13 4 Modified amino acid residues: Draw 2D NMR spectrum
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11/14/13 5 Modified amino acid residue: Draw structure Suppose that the amino acid residue threonine (structure shown in figure) has been modified and produces the NMR spectrum shown below. Assume that the modification only alters the number and
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Unformatted text preview: arrangements oF carbon atoms. The structure has been changed to have a. One new methyl b. Two new methyls c. A methyl replacing the alpha proton d. A methyl replacing the beta proton 11/14/13 6 Unmodifed Thr Modifed Thr C ! H (unchanged) 3.6 ppm Doublet by C " H C # H (unchanged) 4.3 ppm Doublet of doublet byC ! H and C " H C " H (shifted from 1.3) 3.2 ppm Multiplet by C # H and 2C $ H 3 2C $ H 3 (new) 1.1 and 1.3 ppm 2 doublets by C " H Modifed Thr Conclusion: The amino acid has been modifed to have two new methyl groups attached to the delta position....
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  • Spring '14
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