Lecture21 - Lecture 21 Life History Evolution III Friday...

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Lecture 21: Life History Evolution III Friday, March 7 th Readings: 13.2 (both editions) 1 Extra Office Hour Monday 2-3pm
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Learning Objectives 1. Describe the two hypothesized mechanisms for the evolutionary theory of aging. What type of evidence would you look for to support each of these hypotheses? 2. Explain how ecological mortality is proposed to affect the evolution of senescence.
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Why do animals age? Evolutionary Theory of Aging: Death at old age has little effect on fitness Mechanism 1: The mutation accumulation hypothesis Mechanism 2: The antagonistic pleiotropy hypothesis 3
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Fitness & lifespan a. maturity 3, death 16; lifetime reproductive success: b. maturity 3, death 14; lifetime reproductive success: a. b. (Fig. 13.10) 4
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Mutation accumulation hypothesis Mutations that occur late in life affect few individuals and are not strongly selected against Late acting mutations persist in a population and contribute to senescence Example: Huntington’s disease Autosomal dominant condition Symptoms develop in 30s or 40s 5
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  • Spring '11
  • DAVIDSON
  • Evolution, Senescence, 35%, 5000 years

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