11 Intracellular Components

11 Intracellular Components - Lecture 12 racellular...

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Lecture 12 tracellular Compartments and Transpo I) Transport through Nuclear Pores II) Transport Across Membranes -Mitochondria -ER III) Transport Via Vesicles Endomembrane System IV) Endocytosis
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Review: Some of the instances and needs for waste exchange in cell biology – classical example Red blood cell-mediated transport of CO 2 from the tissues to the lungs
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Low and high O 2 and CO 2 refer to their concentrations, or partial pressures.
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Table 11-1 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 11-1 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 11-2 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 11-18 Molecular Biology of the Cell (© Garland Science 2008)
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Table 11-1 Essential Cell Biology (© Garland Science 2010) Membrane Proteins Serve Many Functions
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Figure 11-21 Essential Cell Biology (© Garland Science 2010) Different Membrane Proteins Association with the Lipid Bilayer Reflects Theirs Cellular Functions
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Figure 11-39 Essential Cell Biology (© Garland Science 2010) Cell Surface Carbohydrates Do More Than Prote & Lubricate the Cells Via the Glycocalyx Lectins are proteins of endothelial cells that line blood vessels and help recruit neutrophils via the glycoproteins and glycolipids found on the neutrophils’ cell surface. This binding leads to other protein to protein interactions that allow the neutrophils to slip between endothelial cells and migrate to the site of infection in a tissue.
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Figure 15-1 Essential Cell Biology (© Garland Science 2010) Example of many membranous compartments found in the c
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Table 15-1 Essential Cell Biology (© Garland Science 2010)
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Cell Membranes Are Crucial for the Life of the Cell: Role in Compartmentalization of Eukaryotic Cells
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Table 15-2 Essential Cell Biology (© Garland Science 2010)
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Figure 15-3 Essential Cell Biology (© Garland Science 2010) Hypothesis – Membrane Bound Organelles Originated Possibly From Invagination of the Plasma Membrane
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Figure 15-4 Essential Cell Biology (© Garland Science 2010) Similarly Mitochondria and Chloroplasts Believed Began as Aerobic Prokaryotes Engulfed by a Larger Pre-Eukaryote Cell
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Protein Sorting hree Methods of Importing Proteins into Organelles – ALL Require Energy
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Nobel Prize 2013 The 2013 Nobel Prize honors three scientists who have solved the mystery of how the cell organizes its transport system how protein sorting is accomplished . Each cell is a factory that produces and exports molecules. For instance, insulin is manufactured and released into the blood and chemical signals called neurotransmitters are sent from one nerve cell to another. These molecules are transported around the cell in small packages called vesicles . The three Nobel Laureates have discovered the molecular principles that govern how this cargo is
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