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Unformatted text preview: the incoming substrate first binds at the entry site, then rotates into the active
site where it base pairs with template DNA and the RNAP II tightens its active
RNA synthesized in the 5/-> 3/ direction 6 25. Which of the following statements about the C-terminal domain (CTD) of subunit
Rpb1 of mammalian RNAP II is NOT correct?
a. it provides a binding site for the mRNA capping enzyme
b. it contains 52 highly conserved repeats with the consensus sequence,
c. the CTD must be phosphorylated for transcription elongation to start
d. phosphorylated CTD provides a binding site for cleavage and polyadenylation
e. the phosphorylated CTD provides the major binding site for TFIIB 26. BRE, TATA, Inr, MTE, and DPE and are all:
general transcription factors
specialized transcription factors
core promoter elements for RNA polymerase II
prokaryotic Pribnow box elements 27. Which of the following statements about the protein shown below is NOT correct? a....
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- Spring '13