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Unformatted text preview: of any vitamin(s)
involved in reaction 1
Niacin CoA (d) (1) Stabilized by resonance
CH2 C - O
SCoA - CH2 C SCoA (2) There will also be a (+) charged active site residue or metal cation (Mg+2, Zn+2) prosthetic group
involved in stabilizing the negative charge on the carbanion
16C Fatty acid 8 acetyl CoA SLP = 0
(like succinate dehydrogenase rxn)
8 acetyl CoA 7 x 1.5 = 10.5
7 x 2.5 = 17.5 16 CO2 (TCA cycle) SLP 8x1=8 Oxphos
Succinate 24 x 2.5 = 60
8 x 1.5 = 12
Total =108 But used 1 ATP so net synthesis of ATP = 108-1 = 107
(a) ATC is an allosteric enzyme. This conclusion is derived from an examination of the shape of its activity
curve. It is sigmoidal which indicates cooperative S binding by a multisubunit enzyme.
(b) CTP is a negative effector because when CTP is added the affinity of the E for the S decreases.This is
indicated by the increase in K0.5 in the presence of CTP.
(c) CTP is the eventual product of the biosynthetic pathway; thus when the [CTP]...
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This test prep was uploaded on 04/01/2014 for the course BIOL 201 taught by Professor Chowrira during the Winter '13 term at The University of British Columbia.
- Winter '13