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How do some cells know to stick together, others migrate
to certain places, others become skin, or feather or bone? Cell Adhesion
2 main kinds of cell arrangements
Differential cell adhesion Bicoid gradient in Drosophila Cell adhesion molecules
Many different types of molecules hold cells
Largest class are called the cadherins
Cadherins span the cell membrane and stick
best to the same type (homotypic binding)
Catenins connect cadherins to the actin
cytoskeleton Classical fate mapping Modern cell lineage analysis...
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This document was uploaded on 04/01/2014.
- Spring '10
- Developmental Biology