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Unformatted text preview: and school-age children are too mature.
In thalassemia, immature erythrocytes proliferate, not mature ones. This is a progressive anemia. Defective
hemoglobin is produced as a result of genetically deficient -polypeptide. This hemoglobin is unstable, disintegrates, and
damages the erythrocytes. Rapid destruction of the red cells stimulates rapid production of immature red cells, and the net gain is
less-than-optimally functioning red cells. Iron from the red blood cell destruction is stored in the tissues, causing multiple
problems. The nurse also would note microcytosis and hypochromia. Therefore, options 1, 2, and 4 are incorrect statements.
The female offspring of an affected male and a carrier female are at risk for hemorrhage once puberty is
attained and menstrual cycles begin, and depending on the severity of the hemophilia, a hysterectomy or ablation may be
performed. Options 2, 3, and 4 are incorrect statements. Hemarthrosis is the result of bleeding into the joint cavity, not of...
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- Spring '14