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NSG 210 Test 3 Study Guide

Hbv immune globulin hbig provides passive immunity to

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Unformatted text preview: udes viral & nonviral hepatitis Viral Hepatitis  ­A systemic, viral infection in which necrosis & inflammation of liver cells produce a characteristic cluster of clinical, biochemical & cellular changes. It is easily transmitted & causes high morbidity.  ­There are 5 definitive types of viral hepatitis: A, B, C, D, E. Hepatitis A (HAV) Mode of Transmission: transmitted primarily via fecal ­oral route, by the ingestion of food/liquids infected by the virus. It is more prevalent in countries w/ overcrowding & poor sanitation  ­Also transmitted w/ person to person contact, oral ­anal contact during sex & through food & water.  ­It is seen mainly in other countries, like Mexico where there may be contaminated shellfish, water or other food sources. Also seen in urban areas & day care facilities Ax/Dx: HAV antibodies would be present in the blood if the person is HAV positive. Pt may also exhibit immunoglobulin M (IgM) antibodies that show ongoing inflammation of the liver present 4 ­6 wks in blood, post exposure. Immunoglobulin G (IgG) antibodies may be present & show previous exposure or immunity to HAV.  ­An increase in liver enzymes (AST & ALT), & bilirubin, would be present S/S: Many pts are asymptomatic. When s/s appear, they are flu ­like w/ low grade fever. Anorexia may appear early on. Later, jaundice, dark urine, indigestion, & an aversion to the smell of cigarette smoke may develop.  ­Most pts recover from HAV; it rarely progresses to cirrhosis or liver failure. No carrier state exists  ­Pts w/ HAV are not immune from other types of hepatitis Prevention  ­Handwashing, safe water supplies & proper control of sewage disp...
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