NSG 210 Test 3 Study Guide

The most common cause of damage is malnutrition esp

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Unformatted text preview: n & avoid activity for several hours. 3. Other DX tests: ultrasound, CT scan, MRI are used to identify abnormalities of the liver. Laparoscopy used to perform guided liver biopsy, determine the cause of ascites & to dx tumors in the liver/other abdominal organs General Hepatic Dysfunction Information  ­Liver dysfunction is acute or chronic. Chronic is far more common  ­Acute liver failure characterized by massive necrosis of hepatocytes. Liver is initially enlarged during the acute inflammatory stageatrophy as hepatocellular necrosis advances  ­Acetaminophen toxicity is leading cause of acute liver failure; idiosyncratic drug reactions are second cause.  ­Chronic liver disease: 12th leading cause of death in US among young & middle aged adults  ­Chronic liver disease is twice as common in men as in women.  ­Also more common in Asian/African countries than in Europe or the US.  ­Etiology of liver dysfunction includes: infectious agents (bacteria/viruses), anoxia, metabolic d/o, toxins, medications, nutritional deficiencies & hypersensitivity states.  ­The most common cause of damage is malnutrition, esp r/t alcoholism  ­Most common manifestations of liver disease include jaundice, portal HTN, ascites, varices, nutritional deficiencies, hepatic encephalopathy & coma. HEPATIC DYSFUNCTIONS Jaundice  When serum bilirubin concentration is increasedskin & sclera become yellow ­tinged.  ­Clinically evident when serum bilirubin level exceeds 2.5mg/dL Causes: impairment of hepatic uptake, conjugation of bilirubin, excretion of bilirubin into biliary system Types: hemolytic, hepatocellular*, obstructive jaundice* & hereditary hyberbilirubinemia *Most commonly assc. w/ liver disease Hepatocellular jaundice: caused by the inability of d...
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This document was uploaded on 03/29/2014.

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