genetics and politics 4

genetics and politics 4 - Genetics traits and the Genome...

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Analysis of the human genome. Selective breeding and the evolution of human traits. Man’s impact on evolution. How or can we link human traits to genes? Genetics, traits and the Genome
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Analysis of the Genome Physical vs Genetic analysis The human genome is cloned. We know the map. Not all genes have ascribed function. How do we analyze this physically?
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S ingle N ucleotide P olymorphisms (SNPs) Our genomes are 99.9% identical. There are 3 billion basepairs and 25,000  genes. Still, there are 6 million SNPs already  identified. SNPs identify alleles in the human race. SNPs may be used in personalized medicine. You can have yourself done for < $1000. What experiment did Dr. Hibbing do to link sequences with traits? (It was a physical analysis of the genome. Not the twin studies)
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= genes frequency Line up SNP hits along the  chromosome.  Testing genomes and conservative beliefs. Let us agree on the phenotype. Let us select a method of physical analysis. Let’s do SNPs. We’ll let the stats people help us (but we need to know some stats) Where are the hits?
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Candidate  (not political)  Approach (Have you heard of this before?) What genes did Dr. Fowler study? On what basis did he chose those genes?
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Dr. Fowler took a candidate  approach.
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