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98BFinalKey07Tsai

98BFinalKey07Tsai - Score Bio 98B Final Exam Name SID...

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Bio 98B Final Exam 3/23/07 Name SID Either full names or abbreviations of enzymes/intermediates are fine. ). Name the three enzymes that are NOT irreversible during the first phase of glycolysis (3 pt). _phosphoglucose isomerase (PGI)___ __Aldolase (ALD)______ ___Triose phosphate isomerase (TPI)___ ). During the first step of gluconeogenesis, the enzyme ____pyruvate carboxylase_____ (1 pt) produces the compound ____oxaloacetate (OAA)__ (1 pt) that also appears in the TCA cycle. Draw the structure of this intermediate below (2 pt). Draw chemical structure here. ). Name the two glycolysis enzyme that are activated by fructose-2,6-bisphosphate (F2,6BP) (2 pt). ___pyruvate kinase (PK)___ __phosphofructose kinase (PFK or PFK1)____ ). Two opposing forces are never activated at the same time, this is called ___recipricol control_____ (a two-word phrase) (1 pt) ). Consider a liver cell stimulated with insulin. a) How does it affect the rate of gluconeogenesis in these cells? b) How does it affect the level of fatty acid biosynthesis in these cells? c) What is the effect on glycogen phosphorylase? (Answer a, b and c simply by saying “decrease”, “increase” or “no change”, 3 pt total) (a)____decrease________ (b)_____increase_____ (c)___decrease_____ ). How many net molecules of ATP will one molecule of fructose-1,6-bisphosphate (FBP) generate upon complete oxidation to CO2 and H2O in the muscle? (2 pt) Glucose 32 ATP FBP saves 2 ATP, therefore it is 32 +2 = 34 ATP Score (Do not write in here) Total
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Bio 98B Final Exam 3/23/07 Name SID ). About the prosthetic groups of pyruvate dehydrogenase. vitamin B1 is converted into__TPP____, which is the prosthetic group of __E1__ (answer E1, E2 or E3), while vitamin B3 is converted into ___NAD or NADH___ (3 pt). ). Name the three enzymes that catalyze oxidative decarboxylation: _pyruvate dehydrogenase (PDH)_, __isocitrate dehydrogenase (IDH)__, __ α -ketoglutarate dehydrogenase ( α -KGDH)____(3 pt) ) Match the following enzymes with the appropriate statement. Use each answer once. (5 pt) i. aconitase A. produces isocitrate ii. pyruvate dehydrogenase B. catalyzes a substrate level phosphorylation reaction iii. succinyl CoA synthetase C. is inhibited by both succinyl-CoA and NADH iv. α -ketoglutarate dehydrogenase D. uniquely uses FAD to oxidize its substrate
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