13 12712 epistasi rapporti fenotipici relativi a

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Unformatted text preview: di, modificati a causa di interazioni geniche A_B_ A_bb aaB_ 9:3:3:1 9 3 3 9:3:4 9 3 Rapporto 12 : 3 : 1 9:7 15 : 1 9 1 1 Nessuno Epistasi dominante Epistasi recessiva doppia 7 15 Tipo di interazione Epistasi recessiva 4 3 12 aabb 1 Epistasi dominante doppia NB: presupposto Ogni rapporto deriva da un incrocio diibrido A/a B/b x A/a B/b geni che segregano indipendentemente Controllo del colore del mantello nel topo Agouti nero aguti 14 12/7/12 Controllo del colore del mantello nel topo Molti geni cooperano nel deteminare il colore del mantello nei mammiferi Nel topo, alcuni dei principali geni che determinano il colore del mantello: •  gene A determina la distribuzione del pigmento eumelanina (nero) o feomelanina (giallo) nel pelo A/- agouti; a/a nero •  gene B è coinvolto nella sintesi del pigmento nero eumelanina: allele B/- nero, b/b marrone. A/- C/- b/b => marroni. •  gene C l’allele wt C permette l’espressione del colore, allele c impedisce l’espressione del colore. codifica per l’enzima tirosinasi, un enzima chiave nel...
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