Unformatted text preview: ls renew themselves and generate novel melanocytes. Red represents promuta
posed amplifying cells and green melanocytes.
c/c => albino
Fig. 2. Melanosome development. A: The four stages of melanosome development are shown
Allele c recessivo, sestriated stage provoca assenza del pigmento (fenotipo in stage III and the fully fewer
omozigote, II melanosome, the early deposition of melanin
pigmented stage IV genotipi degli a In geni III melanosomes, the
albino), indipendentemente dai melanosomes. B: ltri stage coinvolti nel colore pigmentation enzymes Tyr, embr
Tyrp1, and Dct reside in the melanosome membrane and catalyze the synthesis of melanin from
tyrosine. The melanin is believed to be deposited onto ﬁbrillar structures formed by the Silver
protein. Currently, it is not known how tyrosine is transported into the melanosome. Several other
proteins reside in the...
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- Fall '14