{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Several other ment proteins reside in the melanosome

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: melanosome membrane, including the Mart1 and Slc24A5 proteins. Their Ednrb function is largely unknown. initia melan or Mitf regulates expression of Kit. Steingrimsson et al., 2004). This path- Of int There is experimental evidence sup- way promotes the interaction of Mitf quire porting both scenarios. It is well es- with the coactivator p300, resulting in melan P A/A C/C a/a c/c Lik tablished in vitro that Kit signals to increased transcriptional activation aguti albino il genotipo c/c Mitf through Map kinase-mediated potential of the èMitf protein. The muta e signaling pathway also results factor F1 phosphorylation of Mitf (reviewed in same pistatico sugli A/a C/c altri geni Gene C, tirosinasi aguti F1 X F1 A/a C/c aguti A/a X A/a C/c X C/c A/a C/c aguti Rapporti F2 combinati Rapporti fenotipici F2 3/4 C/- F2 9/16 A/- C/- 9/16 aguti 1/4 c/c 3/16 A/- c/c 3/16 albini 3/4 C/- 3/16 a/a C/- 3/16 neri 3/4 A/- 4/16 albini 1/4 a/a 1/4 c/c 1/16 a/a c/c Epistasi recessiva: alla F2 rapporto 9:3:4 1/16 albini Epistasi di cc su A/- e a/a 16 12/7/12 Epistasi recessiva F2: 9 neri: 3 marroni: 4 gialli Epistasi recessiva Sistema gruppi sanguigni ABO: Due genitori con gruppo sanguigno 0 hanno avuto un figlio con fenotipo A Come si spiega? L’omozigosi per un allele raro ( h, detto Bombay) di un secondo ge...
View Full Document

{[ snackBarMessage ]}

Ask a homework question - tutors are online