Codifica per lenzima tirosinasi un enzima chiave

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Unformatted text preview: la via biosintetica della melanina Reviews topi omozigoti cc sono albini (assenza melanina), si comportano come recessivi JUNE 1999 (VOL. 5) MOLECULAR MEDICINE TODAY, completi rispetto a ogni altro colore •  gene D controlla l’intensità del pigmento specificato dagli altri geni che controllano il colore (gene modificatore) From pigmentation to obesity addition, melanocortin receptors might act in the central nervous sysHow gene S •  does expression of a pigmentation gene outside the skin cause tem (CNS) to alter behavior16. obesity?controlla la dstribuzioneas an colore sul corpo (ss Melanocortins and melanocortin receptors also play an important Agouti functions in the skin del antagonist of the G = presenza chiazze) protein-coupled receptor Mc1r, one of five known melanocortin receptor subtypes (Mc1–5r)16. Each melanocortin receptor subtype has a distinct domain of expression, as well as unique agonist and antagonist selectivity (Table 1). The agonists for these receptors,...
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This document was uploaded on 04/02/2014.

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