collins_genomicsNature2003

2 avery o t macleod c m mccarty m studies of the

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Unformatted text preview: e will be a living thing, asserting itself with evergrowing insistency” (attributed to Daniel Burnham, architect). ■ Francis S. Collins, Eric D. Green, Alan E. Guttmacher and Mark S. Guyer are at the National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA 1. Mendel, G. Versuche über Pflanzen-Hybriden. Verhandlungen des naturforschenden Vereines, Abhandlungen, Brünn 4, 3–47 (1866). 2. Avery, O. T., MacLeod, C. M. & McCarty, M. Studies of the chemical nature of the substance inducing transformation of pneumococcal types. Induction of transformation by a desoxyribonucleic acid fraction isolated from Pneumococcus Type III. J. Exp. Med. 79, 137–158 (1944). 3. Watson, J. D. & Crick, F. H. C. Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid. Nature 171, 737 (1953). 4. Nirenberg, M. W. The genetic code: II. Sci. Am. 208, 80–94 (1963). 5. Jackson, D. A., Symons, R. H. & Berg, P. Biochemical method for inserting new genetic information into DNA o...
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