collins_genomicsNature2003

E s p e c i a ll y a s t h e y e d u c a t e a ll s e

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Unformatted text preview: n d e rs t a n d i n g o f g e n o m i c s a re n e e d e d . ◆ H i g h - s c h o o l s t u d e n t s w ill b e b o t h t h e u s e rs o f g e n o m i c i n f o r m a t i o n a n d t h e g e n o m i c s re s e a rc h e rs o f t h e f u t ure . E s p e c i a ll y a s t h e y e d u c a t e a ll s e c t o rs o f s o c i e t y, hig h - s c h o ol e d u c a t ors n e e d inf orm a tio n a n d m a t eri a ls a b o ut g e n o m i c s a n d it s im p li c a tio n s f or s o c i e t y, t o u s e in t h e ir c l a s sro o m s . 841 feature tion will be particularly effective. Grand Challenge I-1 describes the ‘functionation’ of the genome, which will increasingly be the critical first step in the development of new therapeutics. But stimulating basic scientists to approach biomedical problems with a genomic attitude is not enough. A therapeutic mindset, lacking in much of academic biomedical research and training, must be explicitly encouraged, and tools developed and provided for its implementation. A particularly promising example of the gene-based approach to therapeutics is the application of ‘chemical genomics’25. This strategy uses libraries of small molecules (natural compounds, aptam...
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