collins_genomicsNature2003

Genomic approaches to the pathogenesis of hematologic

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Unformatted text preview: variation containing 1.42 million single nucleotide polymorphisms. Nature 409, 928–933 (2001). 29. Gabriel, S. B. et al. The structure of haplotype blocks in the human genome. Science 296, 2225–2229 (2002). 30. Reich, D. E. & Lander, E. S. On the allelic spectrum of human disease. Trends Genet. 17, 502–510 (2001). 31. Hirschhorn, J. N., Lohmueller, K., Byrne, E. & Hirschhorn, K. A comprehensive review of genetic association studies. Genet. Med. 4, 45–61 (2002). 32. Wagner, K. R. Genetic diseases of muscle. Neurol. Clin. 20, 645–678 (2002). 33. Golub, T. R. Genomic approaches to the pathogenesis of hematologic malignancy. Curr. Opin. Hematol. 8, 252–261 (2001). 34. Drews, J. & Ryser, S. The role of innovation in drug development. Nature Biotechnol. 15, 1318–1319 (1997). 35. Druker, B. J. Imatinib alone and in combination for chronic myeloid leukemia. Semin. Hematol. 40, 50–8 (2003). 36. Selkoe, D. J. Alzheimer’s disease: genes, proteins, and therapy. Physiol. Rev. 8...
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