Large scale production of genomic data sets the nhgri

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Unformatted text preview: nd feasibility studies, followed by pilot efforts to learn how to apply new strategies and technologies efficiently on a larger scale, and then implementation of full-scale production efforts — will continue to be at the heart of the NHGRI’s priority-setting process. The following are areas of high interest, not listed in priority order. Large-scale production of genomic data sets The NHGRI will continue to support genomic sequencing, focusing on the genomes of mammals, vertebrates, chordates and invertebrates; other funders will support the determination of additional genome sequences from microbes and plants. With current technology, the NHGRI could support the determination of as much as 45–60 gigabases of genomic DNA sequence, or the equivalent of 15–20 human genomes, over the next five years. But as the cost of sequencing continues to decrease, the cost/benefit ratio of sequence generation will improve, so that the actual amount of sequencing done will be greatly affected by the development of improved sequencing technology. The decisions about which genomes to sequenc...
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