collins_genomicsNature2003

Pathways and networks as a complement to the

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Unformatted text preview: rehensive deterNATURE | VOL 422 | 24 APRIL 2003 | www.nature.com/nature mination of all sequence-encoded functional elements in genomes. Proteomics. In the short term, the NHGRI expects to focus on the development of appropriate, scalable technologies for the comprehensive analysis of proteins and protein machines in human health and in both rare and complex diseases. Pathways and networks. As a complement to the development of the genome ‘parts list’ and increasingly effective approaches to proteome analysis, the NHGRI will encourage the development of new technologies that generate a synthetic view of genetic regulatory networks and interacting protein pathways. Genetic contributions to health, disease and drug response. The NHGRI will place a high priority on creating and applying new crosscutting genomics tools, technologies and strategies needed to identify the genetic bases of medically relevant phenotypes. Research on the genetic contributions to rare and common diseases, and to drug response, will typically involve biological systems and diseases of primary interest to othe...
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