Unformatted text preview: rehensive deterNATURE | VOL 422 | 24 APRIL 2003 | www.nature.com/nature mination of all sequence-encoded functional
elements in genomes.
Proteomics. In the short term, the NHGRI
expects to focus on the development of
appropriate, scalable technologies for the
comprehensive analysis of proteins and
protein machines in human health and in
both rare and complex diseases.
Pathways and networks. As a complement
to the development of the genome ‘parts list’
and increasingly effective approaches to proteome analysis, the NHGRI will encourage the
development of new technologies that generate a synthetic view of genetic regulatory
networks and interacting protein pathways.
Genetic contributions to health, disease
and drug response. The NHGRI will place a
high priority on creating and applying new
crosscutting genomics tools, technologies
and strategies needed to identify the genetic
bases of medically relevant phenotypes.
Research on the genetic contributions to rare
and common diseases, and to drug response,
will typically involve biological systems and
diseases of primary interest to othe...
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