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Some of these may seem overly bold but no laws of

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Unformatted text preview: vances in genomics research and its applications to medicine. Some of these may seem overly bold, but no laws of physics need to be violated to achieve them. Such leaps would have profound implications, just as the dreams of the mid-1980s about the complete sequence of the human genome have been realized in the accomplishments now being celebrated. I Genomics to biology Elucidating the structure and function of genomes The broadly available genome sequences of human and a select set of additional organisms represent foundational information for biology and biomedicine. Embedded within this as-yet poorly understood code are the genetic instructions for the entire repertoire of cellular components, knowledge of which is needed to unravel the complexities of biological systems. Elucidating the structure of genomes and identifying the function of the myriad encoded elements will allow connections to be made between genomics and biology and will, in turn, accelerate the exploration of all realms of the biological sciences. For this, new conceptual and technological approaches will be needed to: ◆ Develop a comprehensive and comprehensible c...
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