collins_genomicsNature2003

D e s e a rc h a b l e d a t a b a s e s o f g e n o

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: m a p s a n d s e q u e n c e d a t a b a s e s th a t h a v e a c c e l e r a t e d o t h e r g e n o m i c s re s e a rc h ( e x a m p l e s o f s u c h t o o l s m i g h t i n c l u d e s e a rc h a b l e d a t a b a s e s o f g e n o m i c l e g i s l a t i o n a n d p o l i c i e s fro m a ro u n d t h e w o rl d , o r s t u d i e s o f E L S I a s p e c t s o f i n t ro d u c i n g c l i n i c a l g e n e t i c t e s t s ) ◆ T h e e v a lu a tio n o f n e w g e n e ti c a n d g e n o m i c t e s t s a n d t e c h n o l o g i e s , a n d e ff e c t i v e o v e r s i g h t o f t h e ir i m p l e m e n t a t i o n , t o e n s u r e t h a t o n l y t h o s e w i t h c o n f ir m e d c l i n i c a l v a l i d i t y a r e u s e d f o r p a t i e n t c a re © 2003 Nature Publishing Group Grand Challenge II-1 D e v e l o p ro b u s t s tr a t e g i e s f o r i d e n t i f y i n g t h e g e n e t i c c o n t ri b u t i o n s t o d i s e a s e a n d d r u g r e s p o n s e For common diseases, the interplay of multiple genes and multiple non-genetic factors, not a single allele, usually dictates disease susceptibility and response to treatments. Deciphering the role of genes in human health and disease is a formidable problem for many reasons, including impediments to defining biologically valid phenotypes, ch...
View Full Document

Ask a homework question - tutors are online