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Esdin LS 2 Lec 10 Digestive

Juice 11 42113 pancreas mixed gland that contain both

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Unformatted text preview: ar, parotid •  Pancreas •  Liver •  Gallbladder The Pancreas Stomach Duodenum final destination of food Duct cells secrete NaHCO3 neutralizes stomach acid Acinar cells secrete pancreatic juice produce enzymes (panc. juice) 11 4/21/13 Pancreas •  Mixed gland that contain both endocrine and exocrine tissue •  The exocrine tissue contains two types of cells –  Acinar cells release pancreatic juice –  Duct cells release bicarbonate (HCO3-) Acinar Cells •  Acinar cells release three classes of enzymes into the duodenal lumen –  Proteolytic enzymes: trypsinogen, chymotrypsinogen, and procarboxypeptidase inactive for (pro prefix) –  Pancreatic amylase (digest polysaccharides into disaccharides) –  Pancreatic lipase (digest triglycerides into glycerol and fatty acids) •  Needs bile from the liver to perform its function 12 4/21/13 What Triggers the Pancreas to Release its contents? •  Two hormones released from the duodenum mixed endocrine organ (also releases hormones) –  Secretin acts on duct cells –  Cholecystokinin (CCK) acts on acinar cells activates them What Triggers the Pancreas to self-regulating Release its contents? Acid Protein and fat duct acinar Neutralize the acid Duodenal cells release secretin Duodenal cells release CCK Duct cells Acinar cells NaHCO3 release appetite surpressant Pancreatic juice release secretin when acidic, makes duct cells create bicarbonate to neutralize acid presence of protein leads to CCK, makes acinar cells release enzymes 13 4/21/13 The Liver •  Hepatocytes of the liver release bile salts that functions in fat emulsification –  The break down of large fat droplets into smaller ones a little stored in liver •  Bile salts are stored in the gall bladder bile: not an enzyme, but makes pancreatic lipase more efficient Emulsification Fat globule Bile salts Smaller fat droplets 14 4/21/13 Pathway of Food Salivary glands Mouth Esophagus Gall bladder Liver Stomach Small intestine Pancreas Large intestine Anus The Small Intestine increased surface area villi is plural 15 4/21/13 The Small Intestine •  The small intestine is made of three parts: duodenum, jejunum, and ileum DJ Ileum •  Bile and pancreatic enzymes are released into the duodenum •  The circular folds of...
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