151.L1.Lect7.Kidney.11.22.13.Stu

14 campbell figure 4414 filtration from blood to

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Unformatted text preview: ll Figure 44.14 FILTRATION: - from blood to filtrate Filtrate: Water, NaCl, vitamins, glucose, UREA, amino acids, etc. Flow driven by blood pressure Glomerulus Glomerular capillaries ~100 times leakier than typical capillaries - allows molecules <7kD to be filtered out of blood ….. ………………………. Campbell Figure 44.15 Refinement of kidney (renal) filtrate in the proximal tubule: re-absorption Note the Na+/K+ pumps (1) on the baso-lateral Aquaporin-1 membrane setting up a low [Na+] in the nephron epithelial cells (thus an electrochemical gradient) just as in the GLUT2 enterocytes in the small intestine to enable efficient absorption or re-absorption in this case. Counter-current flow in blood vessel ….. ………………………. Campbell Figure 44.15 Amino acids Na+ AAs cotransporter Refinement of kidney (renal) filtrate in the proximal tubule: re-absorption Note the Na+/K+ pumps (1) on the baso-lateral Aquaporin-1 membrane setting up a low [Na+] in the nephron epithelial cells (thus an electroAmino acid chemical transporter gradient) just as in the enterocytes in the small intestine to enable efficien...
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This note was uploaded on 04/02/2014 for the course BIO 151 taught by Professor Grinblat during the Spring '08 term at University of Wisconsin.

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