Lecture 3

Lecture 3 - Lecture 3 Three principles of differential gene...

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±²³´²±´ ± -FDUVSF ´µ ±²³³²±´ -FBSOJOH HPBMT #Z UIF FOE PG UIF MFDUVSFT BOE BDUJWJUJFT GPS $IBQUFS ³¶ ·$PNQBSF JOGPSNBUJPO DPOUFOU PG EJGGFSFOU HFOPNFT GSPN HFOPNJD EBUB¸ ·3FDPHOJ[F UIF GVODUJPOT PG EJGGFSFOU QPSUJPOT PG UIF HFOPNF¸ ·"QQMZ UIF DPODFQU PG DPNCJOBUPSJBMDPOUSPM UP FYQMBJO UIF SFHVMBUJPO PG HFOF FYQSFTTJPO EVSJOH EFWFMPQNFOU¸ 5ISFF QSJODJQMFT PG EJGGFSFOUJBM HFOF FYQSFTTJPO ±¹ &WFSZ DFMM DPOUBJOT UIF DPNQMFUF HFOPNF FTUBCMJTIFE JO UIF GFSUJMJ[FE FHH¸ ³¹ 5IF VOVTFE HFOFT BSF OPU EFTUSPZFE PS NVUBUFEµ UIFZ SFUBJO UIF QPUFOUJBM GPS CFJOH FYQSFTTFE¸ ´¹ 0OMZ B QPSUJPO PG UIF HFOPNF JT FYQSFTTFE JO FBDI DFMM BOE B QPSUJPO PG UIF 3/" TZOUIFTJ[FE JT TQFDJGJD GPS UIBU DFMM UZQF¸ Genome complexi,es and es,mated numbers of genes for various organisms Organism Complexity (Mb) Es7mated Genes Percentage non-Coding* E. coli 5 4,000 ~20% Yeast 10 5,000 ~50% Caenorhabdi7s 19,000 ~80% Drosophila 180 13,000 ~92% Human 3,000 ~40,000 ~99% *based on 1,000 bp as the average length of coding sequence per gene.
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Lecture 3 - Lecture 3 Three principles of differential gene...

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