Lecture 3.ppt

Light puffed regions indicate areas of high tx figure

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Unformatted text preview: located? Light puffed regions indicate areas of high Tx. Figure 1.8a The Biology of Cancer (© Garland Science 2007) Nucleus 1. Chromatin remodeling Many techniques used to study the differences in gene expression in one cell type versus another. Chromatin (DNA-protein complex) Open DNA (Some DNA not closely bound to proteins) 2. Transcription Primary transcript (pre-mRNA) 3. RNA processing Tail Cap Mature mRNA Cytoplasm 4. mRNA stability Degraded mRNA (mRNA lifespan varies) 5. Translation mRNA Polypeptide 6. Post-translational modification (folding, transport, activation, degradation of protein) Active protein 3...
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This document was uploaded on 04/03/2014.

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