Lecture 5

9 enhancer region modularity enhancers are modular

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Unformatted text preview: on modularity Enhancers are MODULAR and work in COMBINATION with other transcription factors. 5.12 Modular transcriptional regulatory regions using Pax6 as an activator Crystallin gene activated by interaction of Pax 6 with Sox2 and Maf Rat Somatostatin gene activated by Pax6 and Pdx1 TX factor Pax 6 works with other proteins specific for that tissue to differentially express genes RNA polymerase is stabilized on the promoter site of the DNA by transcription factors recruited by the enhancers 4...
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This document was uploaded on 04/03/2014.

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