Lecture 6

Dna methylation is required for imprinting imprinting

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Unformatted text preview: nes affect not only early development, but also later growth of the embryo. DNA methylation is required for imprintingŐ∂ Imprinting is reversible >> Inherited imprinting is erased during early germ cell development<< Specifically IMPRINTED genes (methylation marks on select genes) are NOT disturbed Genome wide de and remethylation From Nature Reviews Genetics 2007 April (8) 253-262 R. Jirtle and M. Skinner 5...
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