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BIO 365R-18-032708 - BIO 365R Continued from last lecture...

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BIO 365R 03/27/08 Continued from last lecture… - monkey experiment neurons changed discharge before a movement is initiated know animal is about to make movement and direction of movement neuron responds more vigorously in yellow direction tuning curve – impulses/sec as a function of direction of movement when the animal makes a particular movement, the preferred direction is the max deviation from preferred direction lowers the response response is modulated based on the preferred direction each neuron causes activity in multiple muscles that are responsible for moving arm from one location to another key point: know neuron fires 40 spikes/sec but can’t tell which movement animal is making, the activity of individual neurons is variable and unpredictable because the tuning is so broad need population (many neurons) for more accurate predictions vector average (picture) – each black line represents a single neuron, length of
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